Dana-Farber Cancer Institute

Response-Based Imaging Endpoints for Recurrent Glioblastoma Clinical Trials

Principal Investigators: Benjamin M. Ellingson, Ph.D., Patrick Wen, M.D., and Timothy F. Cloughesy, M.D.

Institute: University of California, Los Angeles and Dana-Farber Cancer Institute

Initiative: Clinical Trials Endpoints

Location: Los Angeles, CA and Boston, MA

A phase II study of RAD001 (everolimus) for children with chemotherapy hemotherapy-refractory progressive symptomatic low grade gliomas

Principal Investigator: Mark W. Kieran, MD, PhD

Institute: Dana-Farber Cancer Institute

Initiative: Pediatric Low Grade Glioma (LGG) Initiative

Location: Boston, MA

AANS 2009 Translational Research Grant: Promoter methylations in GBM a paradigm beyond methylguanine-DNA MGMT

Principal Investigator: Clark Chen, MD, PhD

Institute: Dana-Farber Cancer Institute

Initiative: Unrestricted Grant

Location: Boston, MA

Establishment of a consortium-based tissue bank dedicated to Pediatric LGA

Principal Investigator: Charles D. Stiles, PhD

Institute: Dana-Farber Cancer Institute

Initiative: Pediatric Low Grade Glioma (LGG) Initiative

Location: Boston, MA

Evaluating the Use of a Complementary Therapy Educational Intervention to Facilitate MRI Procedures for Pediatric Brain Tumor Patients

Principal Investigator: Wendy Wornham, MD

Institute: Dana-Farber Cancer Institute

Initiative: NBTF Complementary and Alternative Medicine Grant

Location: Boston, MA

Identification of genes involved in gliomagenesis of INK4a null mice, Role of the PTEN tumor suppressor in the progression of glioma

Principal Investigator: Ming-Jian You, MD, PhD

Institute: Dana-Farber Cancer Institute

Initiative: Unrestricted Grant

Location: Boston, MA

Identification of the molecular signature of progressive JPA

Principal Investigator: Elizabeth Maher, MD, PhD

Institute: Dana-Farber Cancer Institute

Initiative: Pediatric Low Grade Glioma (LGG) Initiative

Location: Boston, MA

Identifying the Genetic changes associated with recurrent Anaplastic Astrocytoma

Principal Investigator: Elizabeth Maher, MD, PhD

Institute: Dana-Farber Cancer Institute

Initiative: Conneely-Kosinski Anaplastic Astrocytoma Research Fund

Location: Boston, MA

Mitogenic effect of sonic hedgehog in the CNS of transgenic mice

Principal Investigator: David H. Rowitch, MD, PhD

Institute: Dana-Farber Cancer Institute

Initiative: Unrestricted Grant

Location: Boston, MA

Parrafin-based sequencing of the human kinome in pediatric ATRT

Principal Investigator: Mark W. Kieran, MD, PhD

Institute: Dana-Farber Cancer Institute

Initiative: Innovation Research Grant

Location: Boston, MA

Single-cell functional, genomic transcriptonic analysis of glioblastoma

Principal Investigator: Keith L. Ligon, MD, PhD; J. Christopher Love, PhD; and Matthew Meyerson, MD, PhD

Institute: Dana-Farber Cancer Institute

Initiative: The Bridge Project

Location: Boston, MA

Targeting of Olig2 in Oligodendrogliomas

Principal Investigator: Santosh Kesari, MD, PhD

Institute: Dana-Farber Cancer Institute

Initiative: Oligodendroglioma Grant (NBTF)

Location: Boston, MA

Anti-angiogenic gene therapy for brain tumors

Principal Investigator: Lynn Hlatky, PhD

Institute: Dana-Farber Cancer Institute

Initiative: Unrestricted Grant

Location: Boston, MA

Principal Investigator: Lynn Hlatky, PhD

Institute: Dana-Farber Cancer Institute

Initiative: Unrestricted Grant

Location: Boston, MA

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