Phase III Clinical Trials

Potential Brain Tumor Treatments Entering the Pivotal Phase of Evaluation

A large, randomized, controlled Phase III clinical trial is traditionally the last, pivotal step in the evaluation of a potential new medicine before it is approved for use by all patients with the indicated disease. A year ago, the NBTS staff conducted and published a reviewof all the Phase III clinical trials for glioblastoma patients that have been registered with regulators. This became our most read blog of 2017, and to this day continues to be top destination for visitors to this blog. All told, more than 15,000 unique individuals have viewed the post. So, we’ve committed to publishing this feature twice-yearly moving forward – once at the half-way point of the year and once at the end of the year – and expanding the feature beyond glioblastoma to all brain tumor types.

So, below is a list of Phase III clinical trials that are currently enrolling patients to evaluate potential new brain tumor treatments as recorded at the halfway point of 2018.

Many of these are trials of a “novel/investigational agent” – meaning it is the first time a particular treatment is being tried for brain tumor patients. There are also a number of trials with therapies already in use for some brain tumor patients – meaning researchers are evaluating these already-in-use treatments in different combinations, different dosing regimens, or subpopulations of patients.

What follows is a breakdown/overview of the current Phase III brain tumor clinical trial landscape, followed by the full-list of trials with hyperlinks for more information.

Phase III Brain Tumor Clinical Trials Overview

Phase III Clinical Trials with Novel/Investigational Agents

Phase 3 Clinical Trials with Prior/Known Agents

Download the Phase III Clinical Trial Report.

*To support GBM research and help us get to even more potential new glioblastoma treatments faster, please visit here.

*To checkout more clinical trial options, please visit the NBTS Clinical Trial Finder at trials.braintumor.organd check-out yesterday’s post on all the new clinical trials – of any phase – that have opened in recent months, here