News

Glioblastoma Models Get Boost From Cutting-Edge Tech Laboratory models are the backbone of cancer research and the development of new medicines. Researchers use models to study the biology of tumors like glioblastoma (GBM), as well as for testing the potential safety and effectiveness of drugs in different tumor types.  While today’s models for glioblastoma research are the best tools scientists have to […] February 19, 2020

Defeat GBM Research Collaborative: Progress Report (2018-2019) Over the past five years, the Defeat GBM Research Collaborative has stood as a testament to the power of ideas, collaboration, and the philanthropic partnership between patient advocacy nonprofits like NBTS and a dedicated community of supporters.  When we launched Defeat GBM as our flagship research initiative in 2014, we sought to do something different. […] February 10, 2020

Can Newly Approved “Tissue Agnostic” Drugs Benefit Pediatric High-grade Glioma Patients? Recently, the U.S. Food and Drug Administration (FDA) granted accelerated approval* to the drug Rozlytrek (entrectinib, Genentech/Roche**) as a treatment for patients, 12 years or older, whose tumors have a specific genetic defect known as an “NTRK gene fusion.”*** This is now the second drug that the FDA has approved to treat patients with this […] September 16, 2019

A Missing Link to Glioblastoma Growth? An enzyme that serves as a link between oncogenes and the lipids that make-up cells’ membranes may be an important new drug target to treat glioblastoma and other tumors Glioblastoma, like all cancers, develops and progresses as cells begin to multiply and grow out of control, forming a tumor.  Mutations to a protein known as […] August 6, 2019

Gliogene: Confronting the Unknown Through Research As the saying goes, knowledge is power. But, sometimes, it can also be scary. “Oh, it’s horrible!” says Carrie Davis about her quest, which she shares with her sister Hadley, to help better understand links between inheritable genes and brain tumors. She continues, “Every time I get a headache I think I have a brain […] July 23, 2019